Daiichi Sankyo H1 Core Operating Profit Jumps 46.9% to ¥221.3 Billion as Enhertu and Datroway Drive 19.7% Revenue Growth

The Tokyo-based drugmaker grew revenue 19.7% to ¥1,167,233 million in the six months to September, while core operating profit jumped 46.9% to ¥221,331 million and profit attributable to owners of the parent rose 15.8% to ¥151,534 million. Its antibody-drug conjugates Enhertu and Datroway drove the gain, helped by a weaker yen, and Daiichi Sankyo kept its full-year forecast of ¥360,000 million of core operating profit.

Daiichi Sankyo H1 FY3/2027 earnings summary

ADCs and the yen lift every line

Daiichi Sankyo Company, Limited (TSE: 4568) reported consolidated results for the first half of FY3/2027, April 1 to September 30, 2026, on October 30, 2026 under IFRS. Revenue rose by about ¥191.9 billion, driven by its global flagship products Enhertu (trastuzumab deruxtecan) and Datroway (datopotamab deruxtecan), with currency adding about ¥73.9 billion. Revenue at Daiichi Sankyo Inc. in the US rose 54.8% to about ¥422.6 billion on Enhertu and Datroway in the US and Europe, and the Asia, South and Central America unit rose 20.9% to about ¥142.5 billion on Enhertu in Brazil, while the Japan unit fell 6.9% to about ¥232.7 billion as Lixiana and other products declined. Research and development spending rose 10.7% to about ¥240.1 billion on investment in its five DXd ADCs, yet core operating profit still rose 46.9% to ¥221,331 million, with currency adding about ¥22.7 billion.

Restructuring cost below the core line; guidance held

Operating profit rose 34.4% to ¥193,795 million after restructuring costs for the EU Specialty Business Unit were booked outside core profit. Profit before tax rose 18.2% to ¥192,855 million and profit attributable to owners of the parent 15.8% to ¥151,534 million, or ¥83.22 per share against ¥70.55. Daiichi Sankyo kept its FY3/2027 forecast of revenue of ¥2,340,000 million (+10.2%), core operating profit of ¥360,000 million (+15.6%), operating profit of ¥320,000 million (+24.0%) and profit attributable to owners of the parent of ¥251,000 million (−10.3%). It raised the interim dividend to ¥50 from ¥39 and plans ¥50 at year end, an annual ¥100 against ¥78. Total assets were ¥4,258,626 million and the equity ratio 41.3%.

Daiichi Sankyo Company, Limited — H1 FY3/2027 (April 1 – September 30, 2026), IFRS, consolidated. Balance-sheet rows compare September 30, 2026 with March 31, 2026; guidance and dividend rows are full-year FY3/2027 against FY3/2026. "—" indicates a figure not disclosed.
MetricH1 FY3/2027H1 FY3/2026Change
Revenue (¥ million)1,167,233975,353+19.7%
Core operating profit (¥ million)221,331150,690+46.9%
Operating profit (¥ million)193,795144,237+34.4%
Pre-tax profit (¥ million)192,855163,217+18.2%
Net profit attrib. to owners of parent (¥ million)151,534130,814+15.8%
Comprehensive income (¥ million)143,679139,509+3.0%
EPS (¥)83.2270.55+18.0%
Total assets (¥ million)4,258,6263,996,285+6.6%
Equity attrib. to owners of parent (¥ million)1,757,6481,684,033+4.4%
Equity ratio41.3%42.1%-0.8 pt
FY3/2027 guidance — revenue (¥ million)2,340,000—+10.2%
FY3/2027 guidance — core operating profit (¥ million)360,000—+15.6%
FY3/2027 guidance — operating profit (¥ million)320,000—+24.0%
FY3/2027 guidance — net profit (¥ million)251,000—-10.3%
Annual dividend per share (¥)100.0078.00+28.2%

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